Vaccination with Minigenes Encoding V(H)-derived Major Histocompatibility Complex Class I–binding Epitopes Activates Cytotoxic T Cells that Ablate Autoantibody-producing B Cells and Inhibit Lupus

Current treatments for autoantibody-mediated diseases, such as lupus, can cause nonspecific immune suppression. In this paper, we used a bioinformatic approach to identify major histocompatibility complex class I–binding epitopes in the heavy chain variable region of anti-DNA antibodies from lupus-p...

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Detalles Bibliográficos
Autores principales: Fan, Guo-Chang, Singh, Ram Raj
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194049/
https://www.ncbi.nlm.nih.gov/pubmed/12235207
http://dx.doi.org/10.1084/jem.20020223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194049/
https://www.ncbi.nlm.nih.gov/pubmed/12235207
http://dx.doi.org/10.1084/jem.20020223

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