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IκB Kinase Signaling Is Essential for Maintenance of Mature B Cells

Nuclear factor (NF)-κB proteins play crucial roles in immune responses and cellular survival. Activation of NF-κB is mediated by the IκB kinase (IKK) complex, which is composed of two kinases, IKK1 and IKK2, and a regulatory subunit termed NF-κB essential modulator (NEMO). IKK2- and NEMO-deficient m...

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Detalles Bibliográficos
Autores principales:	Pasparakis, Manolis, Schmidt-Supprian, Marc, Rajewsky, Klaus
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194059/ https://www.ncbi.nlm.nih.gov/pubmed/12235208 http://dx.doi.org/10.1084/jem.20020907

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