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Interleukin 2 Signaling Is Required for CD4(+) Regulatory T Cell Function

Mice deficient in interleukin (IL)-2 production or the IL-2 receptor α or β chains develop a lethal autoimmune syndrome. CD4(+) regulatory T cells have been shown to prevent autoimmune diseases, allograft rejection, and to down-regulate antibody responses against foreign antigens. To assess the role...

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Detalles Bibliográficos
Autores principales:	Furtado, Gláucia C., de Lafaille, Maria A. Curotto, Kutchukhidze, Nino, Lafaille, Juan J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194060/ https://www.ncbi.nlm.nih.gov/pubmed/12235217 http://dx.doi.org/10.1084/jem.20020190

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