Cargando…

Antigen-dependent Proliferation of CD4(+) CD25(+) Regulatory T Cells In Vivo

The failure of CD25(+) regulatory T cells (T(regs)) to proliferate after T cell receptor (TCR) stimulation in vitro has lead to their classification as naturally anergic. Here we use T(regs) expressing a transgenic TCR to show that despite anergy in vitro, T(regs) proliferate in response to immuniza...

Descripción completa

Detalles Bibliográficos
Autores principales:	Walker, Lucy S.K., Chodos, Anna, Eggena, Mark, Dooms, Hans, Abbas, Abul K.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194065/ https://www.ncbi.nlm.nih.gov/pubmed/12874258 http://dx.doi.org/10.1084/jem.20030315

Ejemplares similares

Cooperative Roles of CTLA-4 and Regulatory T Cells in Tolerance to an Islet Cell Antigen
por: Eggena, Mark P., et al.
Publicado: (2004)

Functional Tolerance is Maintained Despite Proliferation of CD4 T Cells after Encounter with Tissue-derived Antigen
por: Ausubel, Lara J., et al.
Publicado: (2002)

Continuous control of autoimmune disease by antigen-dependent polyclonal CD4(+)CD25(+) regulatory T cells in the regional lymph node
por: Samy, Eileen T., et al.
Publicado: (2005)

Interleukin-2 enhances CD4(+) T cell memory by promoting the generation of IL-7Rα–expressing cells
por: Dooms, Hans, et al.
Publicado: (2007)

Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells
por: Nishikawa, Hiroyoshi, et al.
Publicado: (2005)

Conversion of CD4(+) CD25(−) cells into CD4(+) CD25(+) regulatory T cells in vivo requires B7 costimulation, but not the thymus
por: Liang, Shuang, et al.
Publicado: (2005)

CCR7 is required for the in vivo function of CD4(+) CD25(+) regulatory T cells
por: Schneider, Martin A., et al.
Publicado: (2007)

IL-15 Augments TCR-Induced CD4(+) T Cell Expansion In Vitro by Inhibiting the Suppressive Function of CD25(High) CD4(+) T Cells
por: Van Belle, Tom L., et al.
Publicado: (2012)

Induction of CD4(+)CD25(+)FOXP3(+) Regulatory T Cells during Human Hookworm Infection Modulates Antigen-Mediated Lymphocyte Proliferation
por: Ricci, Natasha Delaqua, et al.
Publicado: (2011)

Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4(+)CD25(+) regulatory T cells is interleukin 10 dependent
por: Kearley, Jennifer, et al.
Publicado: (2005)

CD4(+)CD25(+) T regulatory cells in renal transplantation
por: Cheung, Jason, et al.
Publicado: (2022)

Direct Expansion of Functional CD25(+) CD4(+) Regulatory T Cells by Antigen-processing Dendritic Cells
por: Yamazaki, Sayuri, et al.
Publicado: (2003)

Regulatory CD4(+)CD25(+) T Cells Restrict Memory CD8(+) T Cell Responses
por: Kursar, Mischo, et al.
Publicado: (2002)

CD4(+) CD25(+) Regulatory T Cells Control T Helper Cell Type 1 Responses to Foreign Antigens Induced by Mature Dendritic Cells In Vivo
por: Oldenhove, Guillaume, et al.
Publicado: (2003)

Ex Vivo Generation of Human Alloantigen-Specific Regulatory T Cells from CD4(pos)CD25(high) T Cells for Immunotherapy
por: Peters, Jorieke H., et al.
Publicado: (2008)

Ex Vivo Isolation and Characterization of Cd4(+)Cd25(+) T Cells with Regulatory Properties from Human Blood
por: Dieckmann, Detlef, et al.
Publicado: (2001)

Human Cd25(+)Cd4(+) T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function
por: Levings, Megan K., et al.
Publicado: (2001)

CD4(+)CD25(+) T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion
por: Herman, Ann E., et al.
Publicado: (2004)

Prolonged Survival of Allografts Induced by Mycobacterial Hsp70 Is Dependent on CD4+CD25+ Regulatory T Cells
por: Borges, Thiago J., et al.
Publicado: (2010)

Partial CD25 Antagonism Enables Dominance of Antigen-Inducible CD25(high) FOXP3(+) Regulatory T Cells As a Basis for a Regulatory T Cell-Based Adoptive Immunotherapy
por: Wilkinson, Daniel S., et al.
Publicado: (2017)

The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4(+)CD25(+ )T cells
por: Frey, Oliver, et al.
Publicado: (2005)

CD4(+)CD25(+) Regulatory T Cell Ontogeny and Preferential Migration to the Cecal Tonsils in Chickens
por: Shanmugasundaram, Revathi, et al.
Publicado: (2012)

Cord Blood Derived CD4(+)CD25(high) T Cells Become Functional Regulatory T Cells upon Antigen Encounter
por: Mayer, Elisabeth, et al.
Publicado: (2012)

Role of antigen-specific regulatory CD4(+)CD25(+) T cells in tolerance induction after neonatal IP administration of AAV-hF.IX
por: Shi, Y, et al.
Publicado: (2013)

Preferential Accumulation of Antigen-specific Effector CD4 T Cells at an Antigen Injection Site Involves CD62E-dependent Migration but Not Local Proliferation
por: Reinhardt, R. Lee, et al.
Publicado: (2003)

The control of CD4(+)CD25(+)Foxp3(+ )regulatory T cell survival
por: Pandiyan, Pushpa, et al.
Publicado: (2008)

LAT-mediated signaling in CD4(+)CD25(+) regulatory T cell development
por: Koonpaew, Surapong, et al.
Publicado: (2006)

Immune modulation of CD4(+)CD25(+) regulatory T cells by zoledronic acid
por: Liu, Hsien, et al.
Publicado: (2016)

Percentage and function of CD4(+)CD25(+) regulatory T cells in patients with hyperthyroidism
por: Jiang, Ting-Jun, et al.
Publicado: (2018)

The levels of CD4+CD25+ regulatory T cells in patients with allergic rhinitis
por: Shaoqing, Y., et al.
Publicado: (2018)

Human granzyme B regulatory B cells prevent effector CD4+CD25- T cell proliferation through a mechanism dependent from lymphotoxin alpha
por: Sailliet, Nicolas, et al.
Publicado: (2023)

Hepatitis B envelope antigen increases Tregs by converting CD4+CD25(-) T cells into CD4(+)CD25(+)Foxp3(+) Tregs
por: Tang, Rui, et al.
Publicado: (2020)

Immunologic Self-Tolerance Maintained by Cd25(+)Cd4(+)Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
por: Takahashi, Takeshi, et al.
Publicado: (2000)

Antigen Specific Tolerance Inhibits Autoimmune Uveitis in Pre-sensitized Animals via Deletion and CD4(+)CD25(+) T-Regulatory Cells
por: Matta, Bharati, et al.
Publicado: (2009)

Murine Melanoma-Infiltrating Dendritic Cells Are Defective in Antigen Presenting Function Regardless of the Presence of CD4(+)CD25(+) Regulatory T Cells
por: Ataera, Haley, et al.
Publicado: (2011)

TLR5 Signaling Enhances the Proliferation of Human Allogeneic CD40-Activated B Cell Induced CD4(hi)CD25(+) Regulatory T Cells
por: Chan, Ping-Lung, et al.
Publicado: (2013)

CD4(+)CD25(+)CD127(−) and CD4(+)CD25(+)Foxp3(+) Regulatory T Cell Subsets in Mediating Autoimmune Reactivity in Systemic Lupus Erythematosus Patients
por: Żabińska, Marcelina, et al.
Publicado: (2016)

Downregulation of CD4+LAP+ and CD4+CD25+ Regulatory T Cells in Acute Coronary Syndromes
por: Lin, Ying-zhong, et al.
Publicado: (2013)

CD4(+)CD25(high)CD127(-) regulatory T-cells in COPD: smoke and drugs effect
por: Chiappori, Alessandra, et al.
Publicado: (2016)

HSP70 Enhances Immunosuppressive Function of CD4(+)CD25(+)FoxP3(+) T Regulatory Cells and Cytotoxicity in CD4(+)CD25(−) T Cells
por: Wachstein, Julian, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_rbpd55iagv7i60m12napvnctjf