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Potent Immune Response against HIV-1 and Protection from Virus Challenge in hu-PBL-SCID Mice Immunized with Inactivated Virus-pulsed Dendritic Cells Generated in the Presence of IFN-α
A major challenge of AIDS research is the development of therapeutic vaccine strategies capable of inducing the humoral and cellular arms of the immune responses against HIV-1. In this work, we evaluated the capability of DCs pulsed with aldrithiol-2–inactivated HIV-1 in inducing a protective antivi...
Autores principales: | Lapenta, Caterina, Santini, Stefano M., Logozzi, Mariantonia, Spada, Massimo, Andreotti, Mauro, Di Pucchio, Tiziana, Parlato, Stefania, Belardelli, Filippo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194078/ https://www.ncbi.nlm.nih.gov/pubmed/12874266 http://dx.doi.org/10.1084/jem.20021924 |
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