Reduced Self-Reactivity of an Autoreactive T Cell After Activation with Cross-reactive Non–Self-Ligand

Autoreactive CD4(+) T lymphocytes are critical to the induction of autoimmune disease, but because of the degenerate nature of T cell receptor (TCR) activation such receptors also respond to other ligands. Interaction of autoreactive T cells with other non–self-ligands has been shown to activate and...

Descripción completa

Detalles Bibliográficos
Autores principales: Munder, Markus, Bettelli, Estelle, Monney, Laurent, Slavik, Jacqueline M., Nicholson, Lindsay B., Kuchroo, Vijay K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194103/
https://www.ncbi.nlm.nih.gov/pubmed/12417626
http://dx.doi.org/10.1084/jem.20020390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194103/
https://www.ncbi.nlm.nih.gov/pubmed/12417626
http://dx.doi.org/10.1084/jem.20020390

Ejemplares similares