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Reduced Self-Reactivity of an Autoreactive T Cell After Activation with Cross-reactive Non–Self-Ligand

Autoreactive CD4(+) T lymphocytes are critical to the induction of autoimmune disease, but because of the degenerate nature of T cell receptor (TCR) activation such receptors also respond to other ligands. Interaction of autoreactive T cells with other non–self-ligands has been shown to activate and...

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Detalles Bibliográficos
Autores principales:	Munder, Markus, Bettelli, Estelle, Monney, Laurent, Slavik, Jacqueline M., Nicholson, Lindsay B., Kuchroo, Vijay K.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194103/ https://www.ncbi.nlm.nih.gov/pubmed/12417626 http://dx.doi.org/10.1084/jem.20020390

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