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Blockade of Inflammation and Airway Hyperresponsiveness in Immune-sensitized Mice by Dominant-Negative Phosphoinositide 3-Kinase–TAT

Phosphoinositide 3-kinase (PI3K) is thought to contribute to the pathogenesis of asthma by effecting the recruitment, activation, and apoptosis of inflammatory cells. We examined the role of class IA PI3K in antigen-induced airway inflammation and hyperresponsiveness by i.p. administration into mice...

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Detalles Bibliográficos
Autores principales:	Myou, Shigeharu, Leff, Alan R., Myo, Saori, Boetticher, Evan, Tong, Jiankun, Meliton, Angelo Y., Liu, Jie, Munoz, Nilda M., Zhu, Xiangdong
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194122/ https://www.ncbi.nlm.nih.gov/pubmed/14623911 http://dx.doi.org/10.1084/jem.20030298

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