A Fail-safe Mechanism for Negative Selection of Isotype-switched B Cell Precursors Is Regulated by the Fas/FasL Pathway

In B lymphocytes, immunoglobulin (Ig)M receptors drive development and construction of naive repertoire, whereas IgG receptors promote formation of the memory B cell compartment. This isotype switching process requires appropriate B cell activation and T cell help. In the absence of T cell help, act...

Descripción completa

Detalles Bibliográficos
Autores principales: Seagal, Jane, Edry, Efrat, Keren, Zohar, Leider, Nira, Benny, Ofra, Machluf, Marcelle, Melamed, Doron
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194123/
https://www.ncbi.nlm.nih.gov/pubmed/14623914
http://dx.doi.org/10.1084/jem.20030357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194123/
https://www.ncbi.nlm.nih.gov/pubmed/14623914
http://dx.doi.org/10.1084/jem.20030357

Ejemplares similares