Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance: Abrogation Prevents Tumor Recurrence

Our previous work demonstrated that cytotoxic T lymphocyte (CTL)-mediated tumor immunosurveillance of the 15-12RM tumor could be suppressed by a CD1d-restricted lymphocyte, most likely a natural killer (NK) T cell, which produces interleukin (IL)-13. Here we present evidence for the effector element...

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Detalles Bibliográficos
Autores principales: Terabe, Masaki, Matsui, So, Park, Jong-Myun, Mamura, Mizuko, Noben-Trauth, Nancy, Donaldson, Debra D., Chen, Wanjun, Wahl, Sharon M., Ledbetter, Steven, Pratt, Bruce, Letterio, John J., Paul, William E., Berzofsky, Jay A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194133/
https://www.ncbi.nlm.nih.gov/pubmed/14657224
http://dx.doi.org/10.1084/jem.20022227

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