Cutaneous Immunization Rapidly Activates Liver Invariant Vα14 NKT Cells Stimulating B-1 B Cells to Initiate T Cell Recruitment for Elicitation of Contact Sensitivity

T cell recruitment to elicit contact sensitivity (CS) requires a CS-initiating process mediated by B-1 cells that produce IgM, which activates complement to promote T cell passage into the tissues. We now show that Vα14i NKT cells induce B-1 cell activation likely by releasing IL-4 early postimmuniz...

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Detalles Bibliográficos
Autores principales: Campos, Regis A., Szczepanik, Marian, Itakura, Atsuko, Akahira-Azuma, Moe, Sidobre, Stephane, Kronenberg, Mitchell, Askenase, Philip W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194147/
https://www.ncbi.nlm.nih.gov/pubmed/14676294
http://dx.doi.org/10.1084/jem.20021562

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