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CB(1) receptor-dependent and -independent inhibition of excitatory postsynaptic currents in the hippocampus by WIN 55,212-2

We investigated the effect of a synthetic cannabinoid, WIN 55,212-2 on excitatory postsynaptic currents (EPSCs) evoked by stimulation of Schaffer collaterals in CA1 pyramidal cells. Bath application of WIN 55,212-2 reduced the amplitude of EPSCs in dose-dependent manner tested between 0.01 nM and 30...

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Detalles Bibliográficos
Autores principales:	Németh, Beáta, Ledent, Catherine, Freund, Tamás F., Hájos, Norbert
Formato:	Texto
Lenguaje:	English
Publicado:	Pergamon Press 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194164/ https://www.ncbi.nlm.nih.gov/pubmed/17714744 http://dx.doi.org/10.1016/j.neuropharm.2007.07.003

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