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Thymic Medullary Epithelial Cell Differentiation, Thymocyte Emigration, and the Control of Autoimmunity Require Lympho–Epithelial Cross Talk via LTβR

Thymocytes depend on the interaction with thymic epithelial cells for the generation of a diverse, nonautoreactive T cell repertoire. In turn, thymic epithelial cells acquire their three-dimensional cellular organization via instructive signals from developing thymocytes. The nature of these signals...

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Detalles Bibliográficos
Autores principales: Boehm, Thomas, Scheu, Stefanie, Pfeffer, Klaus, Bleul, Conrad C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194183/
https://www.ncbi.nlm.nih.gov/pubmed/12953095
http://dx.doi.org/10.1084/jem.20030794