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Continuous Activation of Autoreactive CD4(+) CD25(+) Regulatory T Cells in the Steady State

Despite a growing interest in CD4(+) CD25(+) regulatory T cells (T(reg)) that play a major role in self-tolerance and immunoregulation, fundamental parameters of the biology and homeostasis of these cells are poorly known. Here, we show that this population is composed of two T(reg) subsets that hav...

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Detalles Bibliográficos
Autores principales: Fisson, Sylvain, Darrasse-Jèze, Guillaume, Litvinova, Elena, Septier, Franck, Klatzmann, David, Liblau, Roland, Salomon, Benoît L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194185/
https://www.ncbi.nlm.nih.gov/pubmed/12939344
http://dx.doi.org/10.1084/jem.20030686