Cargando…
Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment
Little is known about the biochemical environment in phagosomes harboring an infectious agent. To assess the state of this organelle we captured the transcriptional responses of Mycobacterium tuberculosis (MTB) in macrophages from wild-type and nitric oxide (NO) synthase 2–deficient mice before and...
Autores principales: | Schnappinger, Dirk, Ehrt, Sabine, Voskuil, Martin I., Liu, Yang, Mangan, Joseph A., Monahan, Irene M., Dolganov, Gregory, Efron, Brad, Butcher, Philip D., Nathan, Carl, Schoolnik, Gary K. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194186/ https://www.ncbi.nlm.nih.gov/pubmed/12953091 http://dx.doi.org/10.1084/jem.20030846 |
Ejemplares similares
-
Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosis
: Signaling Roles of Nitric Oxide Synthase-2 and Phagocyte Oxidase
por: Ehrt, Sabine, et al.
Publicado: (2001) -
Inhibition of Respiration by Nitric Oxide Induces a Mycobacterium tuberculosis Dormancy Program
por: Voskuil, Martin I., et al.
Publicado: (2003) -
MyD88 Primes Macrophages for Full-Scale Activation by Interferon-γ yet Mediates Few Responses to Mycobacterium tuberculosis
por: Shi, Shuangping, et al.
Publicado: (2003) -
Simultaneous Analysis of Multiple Mycobacterium tuberculosis Knockdown Mutants In Vitro and In Vivo
por: Blumenthal, Antje, et al.
Publicado: (2010) -
Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation
por: Xu, Yuanyuan, et al.
Publicado: (2023)