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Impaired T Cell Death and Lupus-like Autoimmunity in T Cell–specific Adapter Protein–deficient Mice
T cell–specific adaptor protein (TSAd) is a T lineage–restricted signaling adaptor molecule that is thought to participate in the assembly of intracellular signaling complexes in T cells. Previous studies of TSAd-deficient mice have revealed a role for TSAd in the induction of T cell interleukin 2 s...
Autores principales: | Drappa, Jorn, Kamen, Lynn A., Chan, Elena, Georgiev, Maria, Ashany, Dalit, Marti, Francesc, King, Philip D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194195/ https://www.ncbi.nlm.nih.gov/pubmed/12953096 http://dx.doi.org/10.1084/jem.20021358 |
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