Targeting Platelet–Leukocyte Interactions: Identification of the Integrin Mac-1 Binding Site for the Platelet Counter Receptor Glycoprotein Ibα

The firm adhesion and transplatelet migration of leukocytes on vascular thrombus are dependent on the interaction of the leukocyte integrin Mac-1 (α(M)β(2), CD11b/CD18) and the platelet counter receptor glycoprotein (GP) Ibα. Previous studies have established a central role for the I domain, a stret...

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Detalles Bibliográficos
Autores principales: Ehlers, Raila, Ustinov, Valentin, Chen, Zhiping, Zhang, Xiaobin, Rao, Ravi, Luscinskas, F. William, Lopez, Jose, Plow, Edward, Simon, Daniel I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194217/
https://www.ncbi.nlm.nih.gov/pubmed/14530377
http://dx.doi.org/10.1084/jem.20022181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194217/
https://www.ncbi.nlm.nih.gov/pubmed/14530377
http://dx.doi.org/10.1084/jem.20022181

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