Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

Interleukin (IL)-12 is a heterodimeric cytokine consisting of the p40 and p35 chains encoded on separate chromosomes. Coordinated expression of the two constituent genes is crucial for appropriate immune responses in timing, location, and magnitude. Interferon (IFN)-γ priming of IL-12 production by...

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Detalles Bibliográficos
Autores principales: Liu, Jianguo, Cao, Shanjin, Herman, Lisa M., Ma, Xiaojing
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194226/
https://www.ncbi.nlm.nih.gov/pubmed/14568984
http://dx.doi.org/10.1084/jem.20030026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194226/
https://www.ncbi.nlm.nih.gov/pubmed/14568984
http://dx.doi.org/10.1084/jem.20030026

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