The Adaptor Protein AP-3 Is Required for CD1d-Mediated Antigen Presentation of Glycosphingolipids and Development of Vα14i NKT Cells

Relatively little is known about the pathway leading to the presentation of glycolipids by CD1 molecules. Here we show that the adaptor protein complex 3 (AP-3) is required for the efficient presentation of glycolipid antigens that require internalization and processing. AP-3 interacts with mouse CD...

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Detalles Bibliográficos
Autores principales: Elewaut, Dirk, Lawton, Anna P., Nagarajan, Niranjana A., Maverakis, Emanual, Khurana, Archana, Höning, Stefan, Benedict, Chris A., Sercarz, Eli, Bakke, Oddmund, Kronenberg, Mitchell, Prigozy, Theodore I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194227/
https://www.ncbi.nlm.nih.gov/pubmed/14557411
http://dx.doi.org/10.1084/jem.20030143

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