Prevention of Lipopolysaccharide-induced Microangiopathy by gp49B1: Evidence for an Important Role for gp49B1 Expression on Neutrophils

gp49B1 is expressed on mast cells and inhibits immunoglobulin E–dependent activation and inflammation in vivo. We now show that gp49B1 is expressed on neutrophils and prevents neutrophil-dependent vascular injury in response to lipopolysaccharide (LPS). The intradermal (i.d.) injection of LPS into g...

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Detalles Bibliográficos
Autores principales: Zhou, Joseph S., Friend, Daniel S., Feldweg, Anna M., Daheshia, Massoud, Li, Lin, Austen, K. Frank, Katz, Howard R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194230/
https://www.ncbi.nlm.nih.gov/pubmed/14557414
http://dx.doi.org/10.1084/jem.20030906

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