Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo

Monocytes can develop into dendritic cells (DCs) that migrate to lymph nodes (LNs) and present antigens to T cells. However, we find that this differentiation is blocked when monocytes accumulate subcutaneously in response to bacteria or lipopolysaccharide (LPS). The inhibition of DC differentiation...

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Detalles Bibliográficos
Autores principales: Rotta, Gianluca, Edwards, Emmerson W., Sangaletti, Sabina, Bennett, Clare, Ronzoni, Simona, Colombo, Mario P., Steinman, Ralph M., Randolph, Gwendalyn J., Rescigno, Maria
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194237/
https://www.ncbi.nlm.nih.gov/pubmed/14568983
http://dx.doi.org/10.1084/jem.20030335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194237/
https://www.ncbi.nlm.nih.gov/pubmed/14568983
http://dx.doi.org/10.1084/jem.20030335

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