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Intracellular Recognition of Lipopolysaccharide by Toll-like Receptor 4 in Intestinal Epithelial Cells

Toll-like receptor (TLR)4 has recently been shown to reside in the Golgi apparatus of intestinal crypt epithelial m-IC(cl2) cells, colocalizing with internalized lipopolysaccharide (LPS). Here we demonstrate that disruption of the integrity of the Golgi apparatus significantly reduced LPS-mediated n...

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Detalles Bibliográficos
Autores principales:	Hornef, Mathias W., Normark, Birgitta Henriques, Vandewalle, Alain, Normark, Staffan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194240/ https://www.ncbi.nlm.nih.gov/pubmed/14568981 http://dx.doi.org/10.1084/jem.20022194

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