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L-Selectin Shedding Does Not Regulate Constitutive T Cell Trafficking but Controls the Migration Pathways of Antigen-activated T Lymphocytes

L-Selectin mediates rolling of lymphocytes in high endothelial venules (HEVs) of peripheral lymph nodes (PLNs). Cross-linking of L-selectin causes proteolytic shedding of its ectodomain, the physiological significance of which is unknown. To determine whether L-selectin shedding regulates lymphocyte...

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Detalles Bibliográficos
Autores principales:	Galkina, Elena, Tanousis, Kyriakos, Preece, Graham, Tolaini, Mauro, Kioussis, Dimitris, Florey, Oliver, Haskard, Dorian O., Tedder, Thomas F., Ager, Ann
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194256/ https://www.ncbi.nlm.nih.gov/pubmed/14597735 http://dx.doi.org/10.1084/jem.20030485

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