Cargando…
GRP94 (gp96) and GRP94 N-Terminal Geldanamycin Binding Domain Elicit Tissue Nonrestricted Tumor Suppression
In chemical carcinogenesis models, GRP94 (gp96) elicits tumor-specific protective immunity. The tumor specificity of this response is thought to reflect immune responses to GRP94-bound peptide antigens, the cohort of which uniquely identifies the GRP94 tissue of origin. In this study, we examined th...
Autores principales: | Baker-LePain, Julie C., Sarzotti, Marcella, Fields, Timothy A., Li, Chuan-Yuan, Nicchitta, Christopher V. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194266/ https://www.ncbi.nlm.nih.gov/pubmed/12461080 http://dx.doi.org/10.1084/jem.20020436 |
Ejemplares similares
-
Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target
por: Duan, Xiaofeng, et al.
Publicado: (2021) -
Expression and clinical significance of Glucose Regulated Proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus
por: Langer, Rupert, et al.
Publicado: (2008) -
Differential requirement of GRP94 and GRP78 in mammary gland development
por: Zhu, Genyuan, et al.
Publicado: (2014) -
Visualization of conformational transition of GRP94 in solution
por: Sun, Shangwu, et al.
Publicado: (2023) -
Structural Insights into Complexes of Glucose-Regulated Protein94 (Grp94) with Human Immunoglobulin G. Relevance for Grp94-IgG Complexes that Form In Vivo in Pathological Conditions
por: Pagetta, Andrea, et al.
Publicado: (2014)