Cargando…

Complex Carbohydrates Are Not Removed During Processing of Glycoproteins by Dendritic Cells: Processing of Tumor Antigen MUC1 Glycopeptides for Presentation to Major Histocompatibility Complex Class II–restricted T Cells

In contrast to protein antigens, processing of glycoproteins by dendritic cells (DCs) for presentation to T cells has not been well studied. We developed mouse T cell hybridomas to study processing and presentation of the tumor antigen MUC1 as a model glycoprotein. MUC1 is expressed on the surface a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vlad, Anda M., Muller, Stefan, Cudic, Mare, Paulsen, Hans, Otvos, Laszlo, Hanisch, Franz-Georg, Finn, Olivera J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194269/ https://www.ncbi.nlm.nih.gov/pubmed/12461079 http://dx.doi.org/10.1084/jem.20020493

Ejemplares similares

Recognition of carbohydrate by major histocompatibility complex class I- restricted, glycopeptide-specific cytotoxic T lymphocytes
Publicado: (1994)

Positional Scanning MUC1 Glycopeptide Library Reveals the Importance of PDTR Epitope Glycosylation for Lectin Binding
por: Singh, YashoNandini, et al.
Publicado: (2019)

Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin
por: Beckwith, Donella M., et al.
Publicado: (2021)

Generation of Novel Anti-MUC1 Monoclonal Antibodies with Designed Carbohydrate Specificities Using MUC1 Glycopeptide Library
por: Naito, Shoichi, et al.
Publicado: (2017)

Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides
por: Rodriguez, Maria C., et al.
Publicado: (2015)

Tyrosine O-GalNAc Alters the Conformation and Proteolytic Susceptibility of APP Model Glycopeptides
por: Singh, YashoNandini, et al.
Publicado: (2021)

MUC1 glycopeptide epitopes predicted by computational glycomics
por: SONG, WEI, et al.
Publicado: (2012)

Roles of adjuvant and route of vaccination in antibody response and protection engendered by a synthetic matrix protein 2-based influenza A virus vaccine in the mouse
por: Mozdzanowska, Krystyna, et al.
Publicado: (2007)

Complex of MUC1, CIN85 and Cbl in Colon Cancer Progression and Metastasis
por: Cascio, Sandra, et al.
Publicado: (2015)

Immunological Evaluation of Recent MUC1 Glycopeptide Cancer Vaccines
por: Hossain, Md Kamal, et al.
Publicado: (2016)

T cell recognition of major histocompatibility complex class II complexes with invariant chain processing intermediates
Publicado: (1995)

Synthetic glycopeptides and glycoproteins with applications in biological research
por: Westerlind, Ulrika
Publicado: (2012)

Urbanization processes drive divergence at the major histocompatibility complex in a common waterbird
por: Pikus, Ewa, et al.
Publicado: (2021)

Carbohydrate moieties of major histocompatibility complex class I alloantigens are not required for their recognition by T lymphocytes
Publicado: (1985)

Introduction of a Glycosylation Site into a Secreted Protein Provides Evidence for an Alternative Antigen Processing Pathway: Transport of Precursors of Major Histocompatability Complex Class I–Restricted Peptides from the Endoplasmic Reticulum to the Cytosol
por: Bačík, Igor, et al.
Publicado: (1997)

Red Queen Processes Drive Positive Selection on Major Histocompatibility Complex (MHC) Genes
por: Ejsmond, Maciej Jan, et al.
Publicado: (2015)

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration
por: Cascio, Sandra, et al.
Publicado: (2013)

Phosphorylated Peptides Are Naturally Processed and Presented by Major Histocompatibility Complex Class I Molecules in Vivo
por: Zarling, Angela L., et al.
Publicado: (2000)

The Major Histocompatibility Complex in Transplantation
por: Ayala García, Marco Antonio, et al.
Publicado: (2012)

Major Histocompatibility Complex in Osteichthyes
por: Stosik, Michał, et al.
Publicado: (2020)

Two Novel Routes of Transporter Associated with Antigen Processing (TAP)-independent Major Histocompatibility Complex Class I Antigen Processing
por: Snyder, Heidi Link, et al.
Publicado: (1997)

Complex Regulatory Networks Governing Production of the Glycopeptide A40926
por: Alduina, Rosa, et al.
Publicado: (2018)

Nonconventional (TL-encoded) major histocompatibility complex molecules present processed viral antigen to cytotoxic T lymphocytes
Publicado: (1991)

Cytoplasmic Processing Is a Prerequisite for Presentation of an Endogenous Antigen by Major Histocompatibility Complex Class II Proteins
por: Lich, John D., et al.
Publicado: (2000)

Identification of Naturally Processed Hepatitis C Virus-Derived Major Histocompatibility Complex Class I Ligands
por: Wölk, Benno, et al.
Publicado: (2012)

Proteasome Subtypes and Regulators in the Processing of Antigenic Peptides Presented by Class I Molecules of the Major Histocompatibility Complex
por: Vigneron, Nathalie, et al.
Publicado: (2014)

Biochemical evidence for the rapid assembly and disassembly of processed antigen-major histocompatibility complex class II complexes in acidic vesicles of B cells
Publicado: (1992)

Early in vivo signaling profiles in MUC1-specific CD4(+) T cells responding to two different MUC1-targeting vaccines in two different microenvironments
por: Reichenbach, Dawn K., et al.
Publicado: (2013)

Synthesis of glycopeptides and glycopeptide conjugates
por: Doelman, Ward, et al.
Publicado: (2022)

Identifying Major Histocompatibility Complex Supertypes
por: Guan, Pingping, et al.
Publicado: (2007)

Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages
por: Shi, Guo-Ping, et al.
Publicado: (2000)

Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy
por: Zhou, Dapeng, et al.
Publicado: (2018)

Major Histocompatibility Complex–linked Control of Autoimmunity
por: Wicker, Linda S.
Publicado: (1997)

The Major Histocompatibility Complex in Bovines: A Review
por: Behl, Jyotsna Dhingra, et al.
Publicado: (2012)

Major histocompatibility complex molecules on glial cells
por: Yong, Voon Wee, et al.
Publicado: (1992)

A bivalent glycopeptide to target two putative carbohydrate binding sites on FimH
por: Lindhorst, Thisbe K, et al.
Publicado: (2010)

Two Distinct Pathways Mediated by PA28 and hsp90 in Major Histocompatibility Complex Class I Antigen Processing
por: Yamano, Taketoshi, et al.
Publicado: (2002)

Interferons and Resistance Mechanisms in Tumors and Pathogen-Driven Diseases—Focus on the Major Histocompatibility Complex (MHC) Antigen Processing Pathway
por: Massa, Chiara, et al.
Publicado: (2023)

RNA assemblages orchestrate complex cellular processes
por: Nielsen, Finn Cilius, et al.
Publicado: (2016)

Specificity of T cell clones for antigen and autologous major histocompatibility complex products determines specificity for foreign major histocompatibility complex products
Publicado: (1983)

Cannot write session to /tmp/vufind_sessions/sess_vlg4ppa74pak7qljstvb9gje29