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Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke

The toll-like receptors (TLRs) are a key component of host defense in the respiratory epithelium. Cigarette smoking is associated with increased susceptibility to infection, while COPD is characterised by bacterial colonisation and infective exacerbations. We found reduced TLR4 gene expression in th...

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Detalles Bibliográficos
Autores principales:	MacRedmond, Ruth E, Greene, Catherine M, Dorscheid, Delbert R, McElvaney, Noel G, O'Neill, Shane J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194695/ https://www.ncbi.nlm.nih.gov/pubmed/18034897 http://dx.doi.org/10.1186/1465-9921-8-84

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