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Models for synthetic biology
Synthetic biological engineering is emerging from biology as a distinct discipline based on quantification. The technologies propelling synthetic biology are not new, nor is the concept of designing novel biological molecules. What is new is the emphasis on system behavior. The objective is the desi...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194732/ https://www.ncbi.nlm.nih.gov/pubmed/17986347 http://dx.doi.org/10.1186/1752-0509-1-47 |
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author | Kaznessis, Yiannis N |
author_facet | Kaznessis, Yiannis N |
author_sort | Kaznessis, Yiannis N |
collection | PubMed |
description | Synthetic biological engineering is emerging from biology as a distinct discipline based on quantification. The technologies propelling synthetic biology are not new, nor is the concept of designing novel biological molecules. What is new is the emphasis on system behavior. The objective is the design and construction of new biological devices and systems to deliver useful applications. Numerous synthetic gene circuits have been created in the past decade, including bistable switches, oscillators, and logic gates, and possible applications abound, including biofuels, detectors for biochemical and chemical weapons, disease diagnosis, and gene therapies. More than fifty years after the discovery of the molecular structure of DNA, molecular biology is mature enough for real quantification that is useful for biological engineering applications, similar to the revolution in modeling in chemistry in the 1950s. With the excitement that synthetic biology is generating, the engineering and biological science communities appear remarkably willing to cross disciplinary boundaries toward a common goal. |
format | Text |
id | pubmed-2194732 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-21947322008-01-15 Models for synthetic biology Kaznessis, Yiannis N BMC Syst Biol Commentary Synthetic biological engineering is emerging from biology as a distinct discipline based on quantification. The technologies propelling synthetic biology are not new, nor is the concept of designing novel biological molecules. What is new is the emphasis on system behavior. The objective is the design and construction of new biological devices and systems to deliver useful applications. Numerous synthetic gene circuits have been created in the past decade, including bistable switches, oscillators, and logic gates, and possible applications abound, including biofuels, detectors for biochemical and chemical weapons, disease diagnosis, and gene therapies. More than fifty years after the discovery of the molecular structure of DNA, molecular biology is mature enough for real quantification that is useful for biological engineering applications, similar to the revolution in modeling in chemistry in the 1950s. With the excitement that synthetic biology is generating, the engineering and biological science communities appear remarkably willing to cross disciplinary boundaries toward a common goal. BioMed Central 2007-11-06 /pmc/articles/PMC2194732/ /pubmed/17986347 http://dx.doi.org/10.1186/1752-0509-1-47 Text en Copyright © 2007 Kaznessis; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Commentary Kaznessis, Yiannis N Models for synthetic biology |
title | Models for synthetic biology |
title_full | Models for synthetic biology |
title_fullStr | Models for synthetic biology |
title_full_unstemmed | Models for synthetic biology |
title_short | Models for synthetic biology |
title_sort | models for synthetic biology |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194732/ https://www.ncbi.nlm.nih.gov/pubmed/17986347 http://dx.doi.org/10.1186/1752-0509-1-47 |
work_keys_str_mv | AT kaznessisyiannisn modelsforsyntheticbiology |