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Interaction of 2-aminopyrimidine with dichloro-[1-alkyl-2-(naphthylazo) imidazole]palladium(II) complexes : Kinetic and mechanistic studies

BACKGROUND: The anticancer properties of cisplatin and palladium(II) complexes stem from the ability of the cis-MCl(2 )fragment to bind to DNA bases. However, cisplatin also interacts with non-cancer cells, mainly through bonding molecules containing -SH groups, resulting in nephrotoxicity. This has...

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Detalles Bibliográficos
Autores principales:	Ghosh, Pradip Kumar, Saha, Sushanta, Mahapatra, Ambikesh
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194761/ https://www.ncbi.nlm.nih.gov/pubmed/17939858 http://dx.doi.org/10.1186/1752-153X-1-23

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