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Characterization of a novel bifunctional mutant of staphylokinase with platelet-targeted thrombolysis and antiplatelet aggregation activities

BACKGROUND: Although staphylokianse (SAK) is among the most promising blood dissolving agents, it is far from ideal. It is interesting to hypothesize that the clot lysis efficacy of SAK can be enhanced with direct active platelet binding ability, and at the same time the rethrombosis complication af...

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Detalles Bibliográficos
Autores principales: Chen, Hongshan, Mo, Wei, Su, Huabo, Zhang, Yanling, Song, Houyan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194782/
https://www.ncbi.nlm.nih.gov/pubmed/17919340
http://dx.doi.org/10.1186/1471-2199-8-88