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Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study analyzing the neurotransmitter/Na(+ )symporter family

BACKGROUND: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. Unfortunately, despite several recent technological advances, structural coverage of membrane integral proteins continues...

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Detalles Bibliográficos
Autores principales: Livesay, Dennis R, Kidd, Patrick D, Eskandari, Sepehr, Roshan, Usman
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194793/
https://www.ncbi.nlm.nih.gov/pubmed/17941992
http://dx.doi.org/10.1186/1471-2105-8-397