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Improved human disease candidate gene prioritization using mouse phenotype
BACKGROUND: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-throughput genome-wide studies like linkage analysis and gene expression profiling, tend to be most useful for classification...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194797/ https://www.ncbi.nlm.nih.gov/pubmed/17939863 http://dx.doi.org/10.1186/1471-2105-8-392 |