Cargando…

EXPERIMENTAL STUDY OF OSMOSIS THROUGH A COLLODION MEMBRANE

Experiments were carried out on a collodion membrane in order to study the factors that determine direction and magnitude of net flow of water across a membrane permeable to the solvent and to some of the solutes present. The solutes used were all non-ionic. When only one solute was present and ther...

Descripción completa

Detalles Bibliográficos
Autores principales: Meschia, Giacomo, Setnikar, Ivo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1958
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194916/
https://www.ncbi.nlm.nih.gov/pubmed/13587923
_version_ 1782147723330322432
author Meschia, Giacomo
Setnikar, Ivo
author_facet Meschia, Giacomo
Setnikar, Ivo
author_sort Meschia, Giacomo
collection PubMed
description Experiments were carried out on a collodion membrane in order to study the factors that determine direction and magnitude of net flow of water across a membrane permeable to the solvent and to some of the solutes present. The solutes used were all non-ionic. When only one solute was present and there was no difference of hydrostatic pressure across the membrane, water flowed toward the side where its vapor pressure was lower, but the rate of transfer depended upon the nature of the solute: for a given difference in osmolality across the membrane, the rate increased with the molecular volume of the solute and reached its maximum with the solute to which the membrane was impermeable. These results led to the experimental demonstration that in the presence of two or more solutes of different molecular volumes, of which one at least can diffuse through the barrier, the net transfer of water can take place against its vapor pressure gradient. Some of the physicochemical and physiological implications of the data are discussed.
format Text
id pubmed-2194916
institution National Center for Biotechnology Information
language English
publishDate 1958
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21949162008-04-23 EXPERIMENTAL STUDY OF OSMOSIS THROUGH A COLLODION MEMBRANE Meschia, Giacomo Setnikar, Ivo J Gen Physiol Article Experiments were carried out on a collodion membrane in order to study the factors that determine direction and magnitude of net flow of water across a membrane permeable to the solvent and to some of the solutes present. The solutes used were all non-ionic. When only one solute was present and there was no difference of hydrostatic pressure across the membrane, water flowed toward the side where its vapor pressure was lower, but the rate of transfer depended upon the nature of the solute: for a given difference in osmolality across the membrane, the rate increased with the molecular volume of the solute and reached its maximum with the solute to which the membrane was impermeable. These results led to the experimental demonstration that in the presence of two or more solutes of different molecular volumes, of which one at least can diffuse through the barrier, the net transfer of water can take place against its vapor pressure gradient. Some of the physicochemical and physiological implications of the data are discussed. The Rockefeller University Press 1958-11-20 /pmc/articles/PMC2194916/ /pubmed/13587923 Text en Copyright © Copyright, 1959, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Meschia, Giacomo
Setnikar, Ivo
EXPERIMENTAL STUDY OF OSMOSIS THROUGH A COLLODION MEMBRANE
title EXPERIMENTAL STUDY OF OSMOSIS THROUGH A COLLODION MEMBRANE
title_full EXPERIMENTAL STUDY OF OSMOSIS THROUGH A COLLODION MEMBRANE
title_fullStr EXPERIMENTAL STUDY OF OSMOSIS THROUGH A COLLODION MEMBRANE
title_full_unstemmed EXPERIMENTAL STUDY OF OSMOSIS THROUGH A COLLODION MEMBRANE
title_short EXPERIMENTAL STUDY OF OSMOSIS THROUGH A COLLODION MEMBRANE
title_sort experimental study of osmosis through a collodion membrane
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194916/
https://www.ncbi.nlm.nih.gov/pubmed/13587923
work_keys_str_mv AT meschiagiacomo experimentalstudyofosmosisthroughacollodionmembrane
AT setnikarivo experimentalstudyofosmosisthroughacollodionmembrane