THE INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON COCAINE AND VERATRINE ACTION IN A VERTEBRATE NERVE

The application of high hydrostatic pressure to toad sciatic nerve causes a gain in sodium and a loss of potassium which are not affected by cocaine. However, cocaine action is enhanced by high pressure when counteracting veratrine depolarization and when blocking the action potential. Various effec...

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Detalles Bibliográficos
Autores principales: Gershfeld, Norman L., Shanes, Abraham M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1959
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194925/
https://www.ncbi.nlm.nih.gov/pubmed/13620893
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author Gershfeld, Norman L.
Shanes, Abraham M.
author_facet Gershfeld, Norman L.
Shanes, Abraham M.
author_sort Gershfeld, Norman L.
collection PubMed
description The application of high hydrostatic pressure to toad sciatic nerve causes a gain in sodium and a loss of potassium which are not affected by cocaine. However, cocaine action is enhanced by high pressure when counteracting veratrine depolarization and when blocking the action potential. Various effects of elevated pressure on the after-potentials are presented and the role of ions in these processes is discussed.
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spelling pubmed-21949252008-04-23 THE INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON COCAINE AND VERATRINE ACTION IN A VERTEBRATE NERVE Gershfeld, Norman L. Shanes, Abraham M. J Gen Physiol Article The application of high hydrostatic pressure to toad sciatic nerve causes a gain in sodium and a loss of potassium which are not affected by cocaine. However, cocaine action is enhanced by high pressure when counteracting veratrine depolarization and when blocking the action potential. Various effects of elevated pressure on the after-potentials are presented and the role of ions in these processes is discussed. The Rockefeller University Press 1959-01-20 /pmc/articles/PMC2194925/ /pubmed/13620893 Text en Copyright © Copyright, 1959, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Gershfeld, Norman L.
Shanes, Abraham M.
THE INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON COCAINE AND VERATRINE ACTION IN A VERTEBRATE NERVE
title THE INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON COCAINE AND VERATRINE ACTION IN A VERTEBRATE NERVE
title_full THE INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON COCAINE AND VERATRINE ACTION IN A VERTEBRATE NERVE
title_fullStr THE INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON COCAINE AND VERATRINE ACTION IN A VERTEBRATE NERVE
title_full_unstemmed THE INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON COCAINE AND VERATRINE ACTION IN A VERTEBRATE NERVE
title_short THE INFLUENCE OF HIGH HYDROSTATIC PRESSURE ON COCAINE AND VERATRINE ACTION IN A VERTEBRATE NERVE
title_sort influence of high hydrostatic pressure on cocaine and veratrine action in a vertebrate nerve
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194925/
https://www.ncbi.nlm.nih.gov/pubmed/13620893
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