Studies on the Role of N-Acetylaspartic Acid in Mammalian Brain

N-Acetylaspartic acid (NAA) occurs at relatively high concentrations exclusively in the mammalian and avian brain and undergoes rapid rise in level soon after birth (Tallan, 1957). The amount of NAA in brains of mentally abnormal human beings and of young human beings was measured. The route by whic...

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Detalles Bibliográficos
Autor principal: Jacobson, K. Bruce
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1959
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194991/
https://www.ncbi.nlm.nih.gov/pubmed/14406413
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author Jacobson, K. Bruce
author_facet Jacobson, K. Bruce
author_sort Jacobson, K. Bruce
collection PubMed
description N-Acetylaspartic acid (NAA) occurs at relatively high concentrations exclusively in the mammalian and avian brain and undergoes rapid rise in level soon after birth (Tallan, 1957). The amount of NAA in brains of mentally abnormal human beings and of young human beings was measured. The route by which NAA is synthesized was shown to involve a direct acetylation of aspartic acid. The degradative activity of the brain toward NAA is slight. Some experiments indicate that NAA in the brain is a physiologically and metabolically active compound.
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spelling pubmed-21949912008-04-23 Studies on the Role of N-Acetylaspartic Acid in Mammalian Brain Jacobson, K. Bruce J Gen Physiol Article N-Acetylaspartic acid (NAA) occurs at relatively high concentrations exclusively in the mammalian and avian brain and undergoes rapid rise in level soon after birth (Tallan, 1957). The amount of NAA in brains of mentally abnormal human beings and of young human beings was measured. The route by which NAA is synthesized was shown to involve a direct acetylation of aspartic acid. The degradative activity of the brain toward NAA is slight. Some experiments indicate that NAA in the brain is a physiologically and metabolically active compound. The Rockefeller University Press 1959-11-01 /pmc/articles/PMC2194991/ /pubmed/14406413 Text en Copyright © Copyright, 1960, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Jacobson, K. Bruce
Studies on the Role of N-Acetylaspartic Acid in Mammalian Brain
title Studies on the Role of N-Acetylaspartic Acid in Mammalian Brain
title_full Studies on the Role of N-Acetylaspartic Acid in Mammalian Brain
title_fullStr Studies on the Role of N-Acetylaspartic Acid in Mammalian Brain
title_full_unstemmed Studies on the Role of N-Acetylaspartic Acid in Mammalian Brain
title_short Studies on the Role of N-Acetylaspartic Acid in Mammalian Brain
title_sort studies on the role of n-acetylaspartic acid in mammalian brain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194991/
https://www.ncbi.nlm.nih.gov/pubmed/14406413
work_keys_str_mv AT jacobsonkbruce studiesontheroleofnacetylasparticacidinmammalianbrain

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