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Osmotic Flow of Water across Permeable Cellulose Membranes
Direct measurements have been made of the net volume flow through cellulose membranes, due to a difference in concentration of solute across the membrane. The aqueous solutions used included solutes ranging in size from deuterated water to bovine serum albumin. For the semipermeable membrane (imperm...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1960
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195087/ https://www.ncbi.nlm.nih.gov/pubmed/13725178 |
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author | Durbin, Richard P. |
author_facet | Durbin, Richard P. |
author_sort | Durbin, Richard P. |
collection | PubMed |
description | Direct measurements have been made of the net volume flow through cellulose membranes, due to a difference in concentration of solute across the membrane. The aqueous solutions used included solutes ranging in size from deuterated water to bovine serum albumin. For the semipermeable membrane (impermeable to the solute) the volume flow produced by the osmotic gradient is equal to the flow produced by the hydrostatic pressure RT ΔC, as given by the van't Hoff relationship. In the case in which the membrane is permeable to the solute, the net volume flow is reduced, as predicted by the theory of Staverman, based on the thermodynamics of the steady state. A means of establishing the amount of this reduction is given, depending on the size of the solute molecule and the effective pore radius of the membrane. With the help of these results, a hypothetical biological membrane moving water by osmotic and hydrostatic pressure gradients is discussed. |
format | Text |
id | pubmed-2195087 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1960 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21950872008-04-23 Osmotic Flow of Water across Permeable Cellulose Membranes Durbin, Richard P. J Gen Physiol Article Direct measurements have been made of the net volume flow through cellulose membranes, due to a difference in concentration of solute across the membrane. The aqueous solutions used included solutes ranging in size from deuterated water to bovine serum albumin. For the semipermeable membrane (impermeable to the solute) the volume flow produced by the osmotic gradient is equal to the flow produced by the hydrostatic pressure RT ΔC, as given by the van't Hoff relationship. In the case in which the membrane is permeable to the solute, the net volume flow is reduced, as predicted by the theory of Staverman, based on the thermodynamics of the steady state. A means of establishing the amount of this reduction is given, depending on the size of the solute molecule and the effective pore radius of the membrane. With the help of these results, a hypothetical biological membrane moving water by osmotic and hydrostatic pressure gradients is discussed. The Rockefeller University Press 1960-11-01 /pmc/articles/PMC2195087/ /pubmed/13725178 Text en Copyright © Copyright, 1961, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Durbin, Richard P. Osmotic Flow of Water across Permeable Cellulose Membranes |
title | Osmotic Flow of Water across Permeable Cellulose Membranes |
title_full | Osmotic Flow of Water across Permeable Cellulose Membranes |
title_fullStr | Osmotic Flow of Water across Permeable Cellulose Membranes |
title_full_unstemmed | Osmotic Flow of Water across Permeable Cellulose Membranes |
title_short | Osmotic Flow of Water across Permeable Cellulose Membranes |
title_sort | osmotic flow of water across permeable cellulose membranes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195087/ https://www.ncbi.nlm.nih.gov/pubmed/13725178 |
work_keys_str_mv | AT durbinrichardp osmoticflowofwateracrosspermeablecellulosemembranes |