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The Biological Mechanisms of Air Ion Action : II. Negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract
Negative air ions are shown to decrease 5-hydroxytryptamine concentrations in extirpated strips of rabbit trachea and in the respiratory tracts of living mice. An initial exposure of guinea pigs to (-) air ions causes a transient rise in urinary 5-hydroxyindoleacetic acid excretion which is not obse...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1960
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195092/ https://www.ncbi.nlm.nih.gov/pubmed/13754552 |
| _version_ | 1782147764529922048 |
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| author | Krueger, Albert P. Smith, Richard F. |
| author_facet | Krueger, Albert P. Smith, Richard F. |
| author_sort | Krueger, Albert P. |
| collection | PubMed |
| description | Negative air ions are shown to decrease 5-hydroxytryptamine concentrations in extirpated strips of rabbit trachea and in the respiratory tracts of living mice. An initial exposure of guinea pigs to (-) air ions causes a transient rise in urinary 5-hydroxyindoleacetic acid excretion which is not observed upon subsequent exposures. These findings are compatible with the hypothesis advanced earlier that (-) air ion effects depend on the ability of (-) ions to accelerate enzymatic oxidation of 5-hydroxytryptamine. |
| format | Text |
| id | pubmed-2195092 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1960 |
| publisher | The Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-21950922008-04-23 The Biological Mechanisms of Air Ion Action : II. Negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract Krueger, Albert P. Smith, Richard F. J Gen Physiol Article Negative air ions are shown to decrease 5-hydroxytryptamine concentrations in extirpated strips of rabbit trachea and in the respiratory tracts of living mice. An initial exposure of guinea pigs to (-) air ions causes a transient rise in urinary 5-hydroxyindoleacetic acid excretion which is not observed upon subsequent exposures. These findings are compatible with the hypothesis advanced earlier that (-) air ion effects depend on the ability of (-) ions to accelerate enzymatic oxidation of 5-hydroxytryptamine. The Rockefeller University Press 1960-11-01 /pmc/articles/PMC2195092/ /pubmed/13754552 Text en Copyright © Copyright, 1961, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Article Krueger, Albert P. Smith, Richard F. The Biological Mechanisms of Air Ion Action : II. Negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract |
| title | The Biological Mechanisms of Air Ion Action : II. Negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract |
| title_full | The Biological Mechanisms of Air Ion Action : II. Negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract |
| title_fullStr | The Biological Mechanisms of Air Ion Action : II. Negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract |
| title_full_unstemmed | The Biological Mechanisms of Air Ion Action : II. Negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract |
| title_short | The Biological Mechanisms of Air Ion Action : II. Negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract |
| title_sort | biological mechanisms of air ion action : ii. negative air ion effects on the concentration and metabolism of 5-hydroxytryptamine in the mammalian respiratory tract |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195092/ https://www.ncbi.nlm.nih.gov/pubmed/13754552 |
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