Activation of the Feeding Reflex in Hydra littoralis : I. Role played by reduced glutathione, and quantitative assay of the feeding reflex

A simple and accurate quantitative assay of the glutathione-activated feeding reflex in Hydra is described. The results show: (a) There are a limited number of receptor-effector systems, probably localized in the area immediately around the mouth and on the tentacles. (b) Concentrations of glutathio...

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Autor principal: Lenhoff, Howard M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1961
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195168/
https://www.ncbi.nlm.nih.gov/pubmed/14463986
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author Lenhoff, Howard M.
author_facet Lenhoff, Howard M.
author_sort Lenhoff, Howard M.
collection PubMed
description A simple and accurate quantitative assay of the glutathione-activated feeding reflex in Hydra is described. The results show: (a) There are a limited number of receptor-effector systems, probably localized in the area immediately around the mouth and on the tentacles. (b) Concentrations of glutathione greater than 5 x 10(-6) M activate all these systems; 10(-5) M glutathione elicits a half-maximum response. (c) Glutathione must be constantly present at the receptor site in order for a response to occur. (d) The response stops in the presence of excess glutathione because of some change within the Hydra, and not as a result of any alteration to the glutathione. The present state of knowledge concerning the mechanism by which glutathione combines with and activates the glutathione receptor to elicit the feeding reflex is summarized.
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spelling pubmed-21951682008-04-23 Activation of the Feeding Reflex in Hydra littoralis : I. Role played by reduced glutathione, and quantitative assay of the feeding reflex Lenhoff, Howard M. J Gen Physiol Article A simple and accurate quantitative assay of the glutathione-activated feeding reflex in Hydra is described. The results show: (a) There are a limited number of receptor-effector systems, probably localized in the area immediately around the mouth and on the tentacles. (b) Concentrations of glutathione greater than 5 x 10(-6) M activate all these systems; 10(-5) M glutathione elicits a half-maximum response. (c) Glutathione must be constantly present at the receptor site in order for a response to occur. (d) The response stops in the presence of excess glutathione because of some change within the Hydra, and not as a result of any alteration to the glutathione. The present state of knowledge concerning the mechanism by which glutathione combines with and activates the glutathione receptor to elicit the feeding reflex is summarized. The Rockefeller University Press 1961-11-01 /pmc/articles/PMC2195168/ /pubmed/14463986 Text en Copyright © Copyright, 1962, by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lenhoff, Howard M.
Activation of the Feeding Reflex in Hydra littoralis : I. Role played by reduced glutathione, and quantitative assay of the feeding reflex
title Activation of the Feeding Reflex in Hydra littoralis : I. Role played by reduced glutathione, and quantitative assay of the feeding reflex
title_full Activation of the Feeding Reflex in Hydra littoralis : I. Role played by reduced glutathione, and quantitative assay of the feeding reflex
title_fullStr Activation of the Feeding Reflex in Hydra littoralis : I. Role played by reduced glutathione, and quantitative assay of the feeding reflex
title_full_unstemmed Activation of the Feeding Reflex in Hydra littoralis : I. Role played by reduced glutathione, and quantitative assay of the feeding reflex
title_short Activation of the Feeding Reflex in Hydra littoralis : I. Role played by reduced glutathione, and quantitative assay of the feeding reflex
title_sort activation of the feeding reflex in hydra littoralis : i. role played by reduced glutathione, and quantitative assay of the feeding reflex
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195168/
https://www.ncbi.nlm.nih.gov/pubmed/14463986
work_keys_str_mv AT lenhoffhowardm activationofthefeedingreflexinhydralittoralisiroleplayedbyreducedglutathioneandquantitativeassayofthefeedingreflex

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