Early Experiments in the Quest of an Active Center in Chymotrypsin

It is now quite proper to speak of an "active site" or "center" in (or on) a number of hydrolytic enzymes, chymotrypsin in particular. Such sites have been clearly demonstrated and in some cases they have even been investigated in detail. We are almost persuaded that they are the...

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Detalles Bibliográficos
Autor principal: Balls, A. K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1962
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195191/
https://www.ncbi.nlm.nih.gov/pubmed/13864462
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author Balls, A. K.
author_facet Balls, A. K.
author_sort Balls, A. K.
collection PubMed
description It is now quite proper to speak of an "active site" or "center" in (or on) a number of hydrolytic enzymes, chymotrypsin in particular. Such sites have been clearly demonstrated and in some cases they have even been investigated in detail. We are almost persuaded that they are the actual loci of enzyme activity in nature. Whatever we think of them, we do know that they are "some peculiar arrangement of amino acids" (2 a).
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spelling pubmed-21951912008-04-23 Early Experiments in the Quest of an Active Center in Chymotrypsin Balls, A. K. J Gen Physiol Article It is now quite proper to speak of an "active site" or "center" in (or on) a number of hydrolytic enzymes, chymotrypsin in particular. Such sites have been clearly demonstrated and in some cases they have even been investigated in detail. We are almost persuaded that they are the actual loci of enzyme activity in nature. Whatever we think of them, we do know that they are "some peculiar arrangement of amino acids" (2 a). The Rockefeller University Press 1962-03-01 /pmc/articles/PMC2195191/ /pubmed/13864462 Text en Copyright © Copyright, 1962, by The Rockefeller Institute Press. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Balls, A. K.
Early Experiments in the Quest of an Active Center in Chymotrypsin
title Early Experiments in the Quest of an Active Center in Chymotrypsin
title_full Early Experiments in the Quest of an Active Center in Chymotrypsin
title_fullStr Early Experiments in the Quest of an Active Center in Chymotrypsin
title_full_unstemmed Early Experiments in the Quest of an Active Center in Chymotrypsin
title_short Early Experiments in the Quest of an Active Center in Chymotrypsin
title_sort early experiments in the quest of an active center in chymotrypsin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195191/
https://www.ncbi.nlm.nih.gov/pubmed/13864462
work_keys_str_mv AT ballsak earlyexperimentsinthequestofanactivecenterinchymotrypsin

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