The Quantitative Interrelationships between Ion Fluxes, Cell Swelling, and Radiation Dose in Ultraviolet Hemolysis

Following treatment with ultraviolet radiation, human red cells leak cations at accelerated rates which depend on the radiation dose. With one exception (initial Na efflux), these accelerated cation fluxes fit the Ussing flux-ratio criterion for passive diffusion. Na efflux is transiently high, but...

Descripción completa

Detalles Bibliográficos
Autor principal: Cook, John S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1965
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195436/
https://www.ncbi.nlm.nih.gov/pubmed/14324984
_version_ 1782147845169610752
author Cook, John S.
author_facet Cook, John S.
author_sort Cook, John S.
collection PubMed
description Following treatment with ultraviolet radiation, human red cells leak cations at accelerated rates which depend on the radiation dose. With one exception (initial Na efflux), these accelerated cation fluxes fit the Ussing flux-ratio criterion for passive diffusion. Na efflux is transiently high, but with time falls to the value expected on the basis of the other cation fluxes. An equation based on the hypothesis of colloid osmotic hemolysis satisfactorily predicts the rate of cell swelling as a result of these ion movements.
format Text
id pubmed-2195436
institution National Center for Biotechnology Information
language English
publishDate 1965
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21954362008-04-23 The Quantitative Interrelationships between Ion Fluxes, Cell Swelling, and Radiation Dose in Ultraviolet Hemolysis Cook, John S. J Gen Physiol Article Following treatment with ultraviolet radiation, human red cells leak cations at accelerated rates which depend on the radiation dose. With one exception (initial Na efflux), these accelerated cation fluxes fit the Ussing flux-ratio criterion for passive diffusion. Na efflux is transiently high, but with time falls to the value expected on the basis of the other cation fluxes. An equation based on the hypothesis of colloid osmotic hemolysis satisfactorily predicts the rate of cell swelling as a result of these ion movements. The Rockefeller University Press 1965-03-01 /pmc/articles/PMC2195436/ /pubmed/14324984 Text en Copyright © 1965 by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Cook, John S.
The Quantitative Interrelationships between Ion Fluxes, Cell Swelling, and Radiation Dose in Ultraviolet Hemolysis
title The Quantitative Interrelationships between Ion Fluxes, Cell Swelling, and Radiation Dose in Ultraviolet Hemolysis
title_full The Quantitative Interrelationships between Ion Fluxes, Cell Swelling, and Radiation Dose in Ultraviolet Hemolysis
title_fullStr The Quantitative Interrelationships between Ion Fluxes, Cell Swelling, and Radiation Dose in Ultraviolet Hemolysis
title_full_unstemmed The Quantitative Interrelationships between Ion Fluxes, Cell Swelling, and Radiation Dose in Ultraviolet Hemolysis
title_short The Quantitative Interrelationships between Ion Fluxes, Cell Swelling, and Radiation Dose in Ultraviolet Hemolysis
title_sort quantitative interrelationships between ion fluxes, cell swelling, and radiation dose in ultraviolet hemolysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195436/
https://www.ncbi.nlm.nih.gov/pubmed/14324984
work_keys_str_mv AT cookjohns thequantitativeinterrelationshipsbetweenionfluxescellswellingandradiationdoseinultraviolethemolysis
AT cookjohns quantitativeinterrelationshipsbetweenionfluxescellswellingandradiationdoseinultraviolethemolysis

Ejemplares similares