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Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium

Electrical activity and histological changes were studied in the degenerating olfactory epithelium of the bullfrog after the olfactory nerve had been sectioned. After nerve section, the electrical responses to odors disappeared in the olfactory epithelium in 8 days in the summer, in 11 days in the e...

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Detalles Bibliográficos
Autores principales: Takagi, Sadayuki F., Yajima, Toshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1965
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195437/
https://www.ncbi.nlm.nih.gov/pubmed/14324975
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author Takagi, Sadayuki F.
Yajima, Toshi
author_facet Takagi, Sadayuki F.
Yajima, Toshi
author_sort Takagi, Sadayuki F.
collection PubMed
description Electrical activity and histological changes were studied in the degenerating olfactory epithelium of the bullfrog after the olfactory nerve had been sectioned. After nerve section, the electrical responses to odors disappeared in the olfactory epithelium in 8 days in the summer, in 11 days in the early autumn, and in 16 days in the early winter. In the degenerating olfactory epithelium a striking decrease in the number of olfactory cells was found, but not of supporting cells. The ratio of the number of olfactory cells to that of supporting cells was found to decrease from 5 or 6 to below 2 after the nerve section. At a ratio below 2, the electrical responses to odor disappeared. The histological changes in the bullfrog are compared with those in the mouse and rabbit. The localization of the olfactory pigment and the electrical activity of the supporting cell are discussed. It was concluded that all three types of responses to odors originate from the activity of the olfactory cell.
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spelling pubmed-21954372008-04-23 Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium Takagi, Sadayuki F. Yajima, Toshi J Gen Physiol Article Electrical activity and histological changes were studied in the degenerating olfactory epithelium of the bullfrog after the olfactory nerve had been sectioned. After nerve section, the electrical responses to odors disappeared in the olfactory epithelium in 8 days in the summer, in 11 days in the early autumn, and in 16 days in the early winter. In the degenerating olfactory epithelium a striking decrease in the number of olfactory cells was found, but not of supporting cells. The ratio of the number of olfactory cells to that of supporting cells was found to decrease from 5 or 6 to below 2 after the nerve section. At a ratio below 2, the electrical responses to odor disappeared. The histological changes in the bullfrog are compared with those in the mouse and rabbit. The localization of the olfactory pigment and the electrical activity of the supporting cell are discussed. It was concluded that all three types of responses to odors originate from the activity of the olfactory cell. The Rockefeller University Press 1965-03-01 /pmc/articles/PMC2195437/ /pubmed/14324975 Text en Copyright © 1965 by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Takagi, Sadayuki F.
Yajima, Toshi
Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium
title Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium
title_full Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium
title_fullStr Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium
title_full_unstemmed Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium
title_short Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium
title_sort electrical activity and histological change in the degenerating olfactory epithelium
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195437/
https://www.ncbi.nlm.nih.gov/pubmed/14324975
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