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Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium
Electrical activity and histological changes were studied in the degenerating olfactory epithelium of the bullfrog after the olfactory nerve had been sectioned. After nerve section, the electrical responses to odors disappeared in the olfactory epithelium in 8 days in the summer, in 11 days in the e...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1965
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195437/ https://www.ncbi.nlm.nih.gov/pubmed/14324975 |
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author | Takagi, Sadayuki F. Yajima, Toshi |
author_facet | Takagi, Sadayuki F. Yajima, Toshi |
author_sort | Takagi, Sadayuki F. |
collection | PubMed |
description | Electrical activity and histological changes were studied in the degenerating olfactory epithelium of the bullfrog after the olfactory nerve had been sectioned. After nerve section, the electrical responses to odors disappeared in the olfactory epithelium in 8 days in the summer, in 11 days in the early autumn, and in 16 days in the early winter. In the degenerating olfactory epithelium a striking decrease in the number of olfactory cells was found, but not of supporting cells. The ratio of the number of olfactory cells to that of supporting cells was found to decrease from 5 or 6 to below 2 after the nerve section. At a ratio below 2, the electrical responses to odor disappeared. The histological changes in the bullfrog are compared with those in the mouse and rabbit. The localization of the olfactory pigment and the electrical activity of the supporting cell are discussed. It was concluded that all three types of responses to odors originate from the activity of the olfactory cell. |
format | Text |
id | pubmed-2195437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1965 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21954372008-04-23 Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium Takagi, Sadayuki F. Yajima, Toshi J Gen Physiol Article Electrical activity and histological changes were studied in the degenerating olfactory epithelium of the bullfrog after the olfactory nerve had been sectioned. After nerve section, the electrical responses to odors disappeared in the olfactory epithelium in 8 days in the summer, in 11 days in the early autumn, and in 16 days in the early winter. In the degenerating olfactory epithelium a striking decrease in the number of olfactory cells was found, but not of supporting cells. The ratio of the number of olfactory cells to that of supporting cells was found to decrease from 5 or 6 to below 2 after the nerve section. At a ratio below 2, the electrical responses to odor disappeared. The histological changes in the bullfrog are compared with those in the mouse and rabbit. The localization of the olfactory pigment and the electrical activity of the supporting cell are discussed. It was concluded that all three types of responses to odors originate from the activity of the olfactory cell. The Rockefeller University Press 1965-03-01 /pmc/articles/PMC2195437/ /pubmed/14324975 Text en Copyright © 1965 by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Takagi, Sadayuki F. Yajima, Toshi Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium |
title | Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium |
title_full | Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium |
title_fullStr | Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium |
title_full_unstemmed | Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium |
title_short | Electrical Activity and Histological Change in the Degenerating Olfactory Epithelium |
title_sort | electrical activity and histological change in the degenerating olfactory epithelium |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195437/ https://www.ncbi.nlm.nih.gov/pubmed/14324975 |
work_keys_str_mv | AT takagisadayukif electricalactivityandhistologicalchangeinthedegeneratingolfactoryepithelium AT yajimatoshi electricalactivityandhistologicalchangeinthedegeneratingolfactoryepithelium |