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Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder
Certain of the metabolic events associated with anaerobic sodium transport by the isolated bladder of the fresh water turtle have been investigated. The data suggest that energy for this transport arises from glycolysis and that endogenous glycogen was the major and perhaps the sole source of substr...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1965
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195440/ https://www.ncbi.nlm.nih.gov/pubmed/14324976 |
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author | Klahr, Saulo Bricker, Neal S. |
author_facet | Klahr, Saulo Bricker, Neal S. |
author_sort | Klahr, Saulo |
collection | PubMed |
description | Certain of the metabolic events associated with anaerobic sodium transport by the isolated bladder of the fresh water turtle have been investigated. The data suggest that energy for this transport arises from glycolysis and that endogenous glycogen was the major and perhaps the sole source of substrate. The rate of anaerobic glycolysis, as determined by lactate formation, correlates well with the rate as determined by glycogen utilization. Using lactate formation as the index of anaerobic glycolysis, a linear relationship was observed between glycolysis and net anaerobic sodium transport. In the absence of sodium transport, glycolysis decreased by approximately 45 per cent. Tissue ATP concentrations were maintained at about the same level under anaerobic as under aerobic conditions. Finally if it is assumed that in the conversion of glycogen to lactate anaerobically, 3 moles of ATP are generated per mole of glucose residue, an average of over 15 equivalents of sodium were transported for every mole of ATP generated. |
format | Text |
id | pubmed-2195440 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1965 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21954402008-04-23 Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder Klahr, Saulo Bricker, Neal S. J Gen Physiol Article Certain of the metabolic events associated with anaerobic sodium transport by the isolated bladder of the fresh water turtle have been investigated. The data suggest that energy for this transport arises from glycolysis and that endogenous glycogen was the major and perhaps the sole source of substrate. The rate of anaerobic glycolysis, as determined by lactate formation, correlates well with the rate as determined by glycogen utilization. Using lactate formation as the index of anaerobic glycolysis, a linear relationship was observed between glycolysis and net anaerobic sodium transport. In the absence of sodium transport, glycolysis decreased by approximately 45 per cent. Tissue ATP concentrations were maintained at about the same level under anaerobic as under aerobic conditions. Finally if it is assumed that in the conversion of glycogen to lactate anaerobically, 3 moles of ATP are generated per mole of glucose residue, an average of over 15 equivalents of sodium were transported for every mole of ATP generated. The Rockefeller University Press 1965-03-01 /pmc/articles/PMC2195440/ /pubmed/14324976 Text en Copyright © 1965 by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Klahr, Saulo Bricker, Neal S. Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder |
title | Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder |
title_full | Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder |
title_fullStr | Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder |
title_full_unstemmed | Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder |
title_short | Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder |
title_sort | energetics of anaerobic sodium transport by the fresh water turtle bladder |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195440/ https://www.ncbi.nlm.nih.gov/pubmed/14324976 |
work_keys_str_mv | AT klahrsaulo energeticsofanaerobicsodiumtransportbythefreshwaterturtlebladder AT brickerneals energeticsofanaerobicsodiumtransportbythefreshwaterturtlebladder |