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Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder

Certain of the metabolic events associated with anaerobic sodium transport by the isolated bladder of the fresh water turtle have been investigated. The data suggest that energy for this transport arises from glycolysis and that endogenous glycogen was the major and perhaps the sole source of substr...

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Detalles Bibliográficos
Autores principales: Klahr, Saulo, Bricker, Neal S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1965
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195440/
https://www.ncbi.nlm.nih.gov/pubmed/14324976
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author Klahr, Saulo
Bricker, Neal S.
author_facet Klahr, Saulo
Bricker, Neal S.
author_sort Klahr, Saulo
collection PubMed
description Certain of the metabolic events associated with anaerobic sodium transport by the isolated bladder of the fresh water turtle have been investigated. The data suggest that energy for this transport arises from glycolysis and that endogenous glycogen was the major and perhaps the sole source of substrate. The rate of anaerobic glycolysis, as determined by lactate formation, correlates well with the rate as determined by glycogen utilization. Using lactate formation as the index of anaerobic glycolysis, a linear relationship was observed between glycolysis and net anaerobic sodium transport. In the absence of sodium transport, glycolysis decreased by approximately 45 per cent. Tissue ATP concentrations were maintained at about the same level under anaerobic as under aerobic conditions. Finally if it is assumed that in the conversion of glycogen to lactate anaerobically, 3 moles of ATP are generated per mole of glucose residue, an average of over 15 equivalents of sodium were transported for every mole of ATP generated.
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spelling pubmed-21954402008-04-23 Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder Klahr, Saulo Bricker, Neal S. J Gen Physiol Article Certain of the metabolic events associated with anaerobic sodium transport by the isolated bladder of the fresh water turtle have been investigated. The data suggest that energy for this transport arises from glycolysis and that endogenous glycogen was the major and perhaps the sole source of substrate. The rate of anaerobic glycolysis, as determined by lactate formation, correlates well with the rate as determined by glycogen utilization. Using lactate formation as the index of anaerobic glycolysis, a linear relationship was observed between glycolysis and net anaerobic sodium transport. In the absence of sodium transport, glycolysis decreased by approximately 45 per cent. Tissue ATP concentrations were maintained at about the same level under anaerobic as under aerobic conditions. Finally if it is assumed that in the conversion of glycogen to lactate anaerobically, 3 moles of ATP are generated per mole of glucose residue, an average of over 15 equivalents of sodium were transported for every mole of ATP generated. The Rockefeller University Press 1965-03-01 /pmc/articles/PMC2195440/ /pubmed/14324976 Text en Copyright © 1965 by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Klahr, Saulo
Bricker, Neal S.
Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder
title Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder
title_full Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder
title_fullStr Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder
title_full_unstemmed Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder
title_short Energetics of Anaerobic Sodium Transport by the Fresh Water Turtle Bladder
title_sort energetics of anaerobic sodium transport by the fresh water turtle bladder
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195440/
https://www.ncbi.nlm.nih.gov/pubmed/14324976
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