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Early T Cell Receptor β Gene Expression Is Regulated by the Pre-T Cell Receptor–CD3 Complex
We have examined the question of whether there is an additional checkpoint in T cell development that regulates T cell receptor (TCR)-β expression in CD25(+)44(−) thymocytes by mechanisms that are independent of the pre-TCR. Our analysis in various mutant mice indicates that all changes in cytoplasm...
Autores principales: | Aifantis, Iannis, Feinberg, Jacqueline, Fehling, Hans Jörg, Di Santo, James P., von Boehmer, Harald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195557/ https://www.ncbi.nlm.nih.gov/pubmed/10429678 |
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