B Cell Development in the Spleen Takes Place in Discrete Steps and Is Determined by the Quality of B Cell Receptor–Derived Signals

Only mature B lymphocytes can enter the lymphoid follicles of spleen and lymph nodes and thus efficiently participate in the immune response. Mature, long-lived B lymphocytes derive from short-lived precursors generated in the bone marrow. We show that selection into the mature pool is an active pro...

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Detalles Bibliográficos
Autores principales: Loder, By Florienne, Mutschler, Bettina, Ray, Robert J., Paige, Christopher J., Sideras, Paschalis, Torres, Raul, Lamers, Marinus C., Carsetti, Rita
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195560/
https://www.ncbi.nlm.nih.gov/pubmed/10429672

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