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Cd4(+) T Cell Division in Irradiated Mice Requires Peptides Distinct from Those Responsible for Thymic Selection

We investigated the mechanism by which α/β T cells expand upon transfer to T cell–deficient host mice by injecting carboxyfluorescein diacetate succinimidyl ester–labeled T cells into mice depleted of T cells by sublethal irradiation. We found that CD4(+) T cells divided when transferred to irradiat...

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Detalles Bibliográficos
Autores principales: Bender, Jeremy, Mitchell, Tom, Kappler, John, Marrack, Philippa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195587/
https://www.ncbi.nlm.nih.gov/pubmed/10430625