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Recombinant Galectin-1 and Its Genetic Delivery Suppress Collagen-Induced Arthritis via T Cell Apoptosis
Galectin-1 (GAL-1), a member of a family of conserved β-galactoside–binding proteins, has been shown to induce in vitro apoptosis of activated T cells and immature thymocytes. We assessed the therapeutic effects and mechanisms of action of delivery of GAL-1 in a collagen-induced arthritis model. A s...
Autores principales: | Rabinovich, Gabriel A., Daly, Gordon, Dreja, Hanna, Tailor, Hitakshi, Riera, Clelia M., Hirabayashi, Jun, Chernajovsky, Yuti |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195592/ https://www.ncbi.nlm.nih.gov/pubmed/10430627 |
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