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Studies in B7-Deficient Mice Reveal a Critical Role for B7 Costimulation in Both Induction and Effector Phases of Experimental Autoimmune Encephalomyelitis

The importance of B7 costimulation in regulating T cell expansion and peripheral tolerance suggests that it may also play a significant regulatory role in the development of autoimmune disease. It is unclear whether B7 costimulation is involved only in the expansion of autoreactive T cells in the pe...

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Detalles Bibliográficos
Autores principales:	Chang, Tammy T., Jabs, Claudia, Sobel, Raymond A., Kuchroo, Vijay K., Sharpe, Arlene H.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1999
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195617/ https://www.ncbi.nlm.nih.gov/pubmed/10477557

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