The B-Oligomer of Pertussis Toxin Deactivates Cc Chemokine Receptor 5 and Blocks Entry of M-Tropic HIV-1 Strains

Infection of target cells by HIV-1 requires initial binding interactions between the viral envelope glycoprotein gp120, the cell surface protein CD4, and one of the members of the seven-transmembrane G protein–coupled chemokine receptor family. Most primary isolates (R5 strains) use chemokine recept...

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Detalles Bibliográficos
Autores principales: Alfano, Massimo, Schmidtmayerova, Helena, Amella, Carol-Ann, Pushkarsky, Tatiana, Bukrinsky, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195621/
https://www.ncbi.nlm.nih.gov/pubmed/10477545

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