Macrophage and Retinal Pigment Epithelium Phagocytosis: Apoptotic Cells and Photoreceptors Compete for αvβ3 and αvβ5 Integrins, and Protein Kinase C Regulates αvβ5 Binding and Cytoskeletal Linkage

Noninflammatory monocyte macrophages use αvβ3 integrin to selectively bind apoptotic cells, initiating their phagocytic removal. In a related process, the retinal pigment epithelium (RPE) employs αvβ5 integrin to recognize spent photoreceptor outer segment particles (OS). Here, we show that apoptoti...

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Detalles Bibliográficos
Autores principales: Finnemann, Silvia C., Rodriguez-Boulan, Enrique
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195631/
https://www.ncbi.nlm.nih.gov/pubmed/10499924

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