Compromised Ox40 Function in Cd28-Deficient Mice Is Linked with Failure to Develop Cxc Chemokine Receptor 5–Positive Cd4 Cells and Germinal Centers

Mice rendered deficient in CD28 signaling by the soluble competitor, cytotoxic T lymphocyte–associated molecule 4–immunoglobulin G1 fusion protein (CTLA4-Ig), fail to upregulate OX40 expression in vivo or form germinal centers after immunization. This is associated with impaired interleukin 4 produc...

Descripción completa

Detalles Bibliográficos
Autores principales: Walker, Lucy S.K., Gulbranson-Judge, Adam, Flynn, Sarah, Brocker, Thomas, Raykundalia, Chandra, Goodall, Margaret, Förster, Reinhold, Lipp, Martin, Lane, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195670/
https://www.ncbi.nlm.nih.gov/pubmed/10523609

Ejemplares similares

Ejemplares similares