Human G Protein–Coupled Receptor Gpr-9-6/Cc Chemokine Receptor 9 Is Selectively Expressed on Intestinal Homing T Lymphocytes, Mucosal Lymphocytes, and Thymocytes and Is Required for Thymus-Expressed Chemokine–Mediated Chemotaxis

TECK (thymus-expressed chemokine), a recently described CC chemokine expressed in thymus and small intestine, was found to mediate chemotaxis of human G protein–coupled receptor GPR-9-6/L1.2 transfectants. This activity was blocked by anti–GPR-9-6 monoclonal antibody (mAb) 3C3. GPR-9-6 is expressed...

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Detalles Bibliográficos
Autores principales: Zabel, Brian A., Agace, William W., Campbell, James J., Heath, Heidi M., Parent, David, Roberts, Arthur I., Ebert, Ellen C., Kassam, Nasim, Qin, Shixin, Zovko, Maria, LaRosa, Gregory J., Yang, Li-Li, Soler, Dulce, Butcher, Eugene C., Ponath, Paul D., Parker, Christina M., Andrew, David P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195678/
https://www.ncbi.nlm.nih.gov/pubmed/10544196

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